Lab News

In press: Dennis’ extensive characterisation of Fluorescent protein behaviour in yeast is published!

Dennis’ work on the behaviour of fluorescent proteins (FPs) in baker’s yeast has been published! With the help of Daan de Groot and Phillipp Schmidt, a variety of fluorescent proteins were characterised for various properties, including brightness, photobleaching, photochromism, day-to-day variation and monomerism. Many FPs showed different performance in yeast compared to previous characterisations done

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Ever thought about the semantic annotation of computational models?

Some of us in the COMBINE community did and this paper is the result: Harmonizing semantic annotations for computational models in biology – Briefings in Bioinformatics – 21 November 2018.

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Julia wins photo competition at the End-of-Summer drinks.

Although the weather still gives the idea that summer didn’t end yet, we had end-of-summer drinks last week. It was a nice get-together and many people joined for a drink and a chat.. The drinks were accompanied by a photo competition with 21 entries. During the drinks the photos were hanging on the wall for

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DAAN DE GROOT WINT NK IN SPIJKENISSE

7-10-2018 Het NK Duathlon werd vandaag een prooi voor Daan de Groot. De Groot trok tijdens het fietsen de wedstrijd naar zich toe. Bij de mannen ging Wesley Mols na het startschot er direct hard vandoor, om met een ruime marge aan het fietsen te kunnen beginnen. Achter hem maakte De Groot samen met Hellas-ploeggenoot

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Bas in action: Outdoor teaching as part of the ActieWeek ‘WOinActie’

Bas recently gave one of his lectures on the campus square as part the ActieWeek ‘WOinActie’ (#WOinActie). This week of protest was an initiative to raise awareness for the workload and lack of funding in Higher Education. Read more about this initiative at https://www.scienceguide.nl/2018/09/een-dure-deken/ (in Dutch) – an opinion piece of AIMMS professor Paola Gori

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Two papers published by Sebastián

Two papers about genome-scale reconstruction and analysis were published by Sebastián Mendoza in March 20th and May 23th. These articles are entitled “Mapping the Physiological Response of Oenococcus oeni to Ethanol Stress Using an Extended Genome-Scale Metabolic Model” and “Traceability, reproducibility and wiki-exploration for “à-la-carte” reconstructions of genome-scale metabolic models“, respectively. Both papers were submitted while Sebastián

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Lab retreat 2018

In the beginning of May we had our yearly lab retreat. This year it was in Blesdijke, all the way up north of the Netherlands, in Friesland. We enjoyed three days of inspiring scientific discussions, great food, swimming in our own pool, live music and exciting games.

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Daan de Groot made it 5th at the 2018 EC Duathlon — Talking about resource allocation!

For those of you who do not know Daan. He is a PhD student in our lab, working on a mathematical theory about optimal metabolism for microbial growth-rate maximisation and its experimental testing. One of the principles underlying his theory is optimal allocation of limited resources for the synthesis of metabolic enzymes. What turns out

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Lab day out in Arnhem

A few weeks ago we had our lab day out and went to Arnhem. We started at Bas’ house for a delicious lunch and enjoyed the beautiful weather in his garden. Then we walked, biked, bussed or drove to the Openluchtmuseum where we spent the afternoon sunbathing, on a tour through the museum, archery and

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Two new papers are out

Recently two new papers were published:   Low affinity uniporter carrier proteins can increase net substrate uptake rate by reducing efflux by Evert Bosdriesz, Meike T Wortel, Jurgen R Haanstra, Marijke J Wagner, Pilar Torre Cortés and Bas Teusink Metabolite Depletion Affects Flux Profiling of Cell Lines by Avlant Nilsson, Jurgen R.  Haanstra, Bas Teusink

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