Lab News

Frank gave his inaugural speech

On Wednesday, June 29, Frank gave his inaugural speech for this University Research Chair in Interdisciplinary Life Sciences. The speech was in Dutch and with it came a written text. The day ended with a party where Frank received two wonderful gifts from the department and other colleagues: a glider (sailplane) flight and a picture of

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Paper on theory of evolution in the chemostat is out

Theoretical work from two former PhD students in the lab, Meike Wortel and Evert Bosdriesz is now published in Nature Scientific Reports (link to paper). It provides a theory that links molecular networks -using metabolic control analysis- and selection pressure in the chemostat. It is also shown that co-existence of fermenters and respirers can occur in population dynamical

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Tutorial on FBA by Bas is online

Bas gave a 1 hour tutorial on stoichiometric modelling and flux balance analysis at the Whole Cell Modelling Course in Barcelona. The lecture was taped. It is really basic, but one of the students from the US told Bas that his talk alone was worth the trip over the ocean. Well, that must have been

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Retreat in Bakkeveen great success

We are just back from our yearly retreat, this year in Bakkeveen, a village in Friesland. We made a list of problems that we tried to solve in teams. Since we have many new experimental people in the team, focus was on concepts and small toy models. Here Bas explains model making to two of the

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Our master program in Bioinformatics and Systems Biology agrees with international standards

A recent paper in Nature Systems Biology and Applications, with Bas as co-author, reports on international workshops held within the ISBE initiative (Infrastructure Europe of Systems Biology) to discuss the curriculum for a Master Program in Systems Biology. Our master program fits these recommendations very well!

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An interview with Bas was published in C2W

C2W is a biweekly magazine published by the KNCV (Royal Netherlands Chemical Society). Bas was interviewed for the latest edition. He talks about his scientific career and discusses current and future goals of the lab’s research. The interview is only available in Dutch. A pdf version of the interview can be viewed here. Image courtesy of

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New paper out co-authored by Jurgen

Jurgen co-authored a paper in BMC genomics that uses mathematical modelling to understand the gene expression cascade in Trypanosoma brucei. You can read it here. The current analysis is a follow-up of two previous publications from Jurgen that describe the contruction of a model of the gene expression cascade in T. brucei (Haanstra et al., 2008)

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A new thesis from our lab by Susanne Roth

Susanne will defend her thesis on May 24 and today we received copies of it! This work is a successful collaboration with the Joachim Goedhart and Dorus Gadella, both from the University of Amsterdam.

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A new review by us is published

You can find it here: Our new Current Opinion in Microbiology Review It discusses how different cultivation methods can be used to select mutant bacteria with improved macroscopic growth parameters and our current understanding of whether such parameters trade off.

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This week we moved to our new building!

For more information see: O2 building information

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