O2 building, room 01W58
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I am investigating the interplay between (heat) stress management and the central carbon metabolism in Bacillus subtilis as part of the AMBER ITN.
When competing for growth rate, microorganisms should maximize their limited amount of resources invested into growth while still maintaining other vital functions in the cell with minimal protein expenditure. This means, a cell that is able to solve the problem of resource allocation optimally will always outgrow its competitors. I want to test whether B. subtilis is able to optimally allocate its resources under stress conditions, specifically heat stress. The experimental results are supplemented with small, tailor made models to understand the underlying mechanisms.
I am a PhD student in Frank Bruggeman’s group as part of the Systems Bioinformatics group of the Teusink lab at the VU University in Amsterdam. Before that, I did a BSc in Bioinformatics and Genome Research in 2011 and a MSc in Genome Based Systems Biology in 2013, both at the Bielefeld University, Germany. During my BSc and MSc theses I have been working on the genetics of flavonoid biosynthesis in Arabidopsis thaliana seeds. In the Teusink lab I am working on Bacillus subtilis.