Pranas Grigaitis


O|2 building, room 01W01


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About me

I obtained my Bachelor’s degree in Biochemistry from Vilnius University (Vilnius, LT) and Master’s in Molecular Biosciences from Heidelberg University (Heidelberg, DE), where I chose Systems Biology as my Major. Both following the mandatory curricula of the studies and driven by my own initiative, I have done internships in institutions like Danish Cancer Research Center (DCRC) or German Cancer Research Center (DKFZ) and acquired a broad spectrum of skills (both wet-lab and computational) there.

Current work

I joined the Systems Biology Lab in July 2019 as a PhD student with prof. Bas Teusink and prof. Ursula Kummer (Heidelberg University, DE) as the promotors. My PhD project was a part of Marie Skłodowska-Curie ITN “SynCrop”, aimed at designing combined computational and experimental strategies to better understand microbial behavior and impact of perturbations in biotechnology-relevant settings.

My PhD research focused on whole-cell modelling of microbes, and, in particular, that of major eukaryotic model organisms Saccharomyces cerevisiae and Schizosaccharomyces pombe. The proteome-constrained models (pc-Models) of these organisms extend the well-established prokaryotic paradigm of resource allocation towards the eukaryotic domain of life. Thus, we can investigate and explain metabolic strategies of eukrayotic organisms in terms of competition for the limited resources at both individual protein- and compartment levels.

In September 2022 I started as a postdoctoral researcher in the HFSP-funded project on multi-omic metabolic modeling of ant colonies.