Pranas Grigaitis

Contact

O|2 building, room 01W01

p.grigaitis[at]vu.nl

ResearchGate profile

About me

I obtained my Bachelor’s degree in Biochemistry from Vilnius University (Vilnius, LT) and Master’s in Molecular Biosciences from Heidelberg University (Heidelberg, DE), where I chose Systems Biology as my Major. Both following the mandatory curricula of the studies and driven by my own initiative, I have done internships in institutions like Danish Cancer Research Center (DCRC) or German Cancer Research Center (DKFZ). Thus, these form a broad spectrum of activities (both wet-lab and computational) I am capable of performing.

Current work

I joined the Systems Biology Lab in July 2019 as a PhD student with prof. Bas Teusink and prof. Ursula Kummer (Heidelberg University, DE) as the promotors. My PhD project is a part of Marie Skłodowska-Curie ITN “SynCrop”, aimed at designing combined computational and experimental strategies to better understand microbial behavior and impact of perturbations in biotechnology-relevant settings.

My current research focuses on whole-cell modelling of microbes, and, in particular, that of major eukaryotic model organisms Saccharomyces cerevisiae and Schizosaccharomyces pombe. The proteome-constrained models (pc-Models) of these organisms extend the well-established prokaryotic paradigm of resource allocation towards the eukaryotic domain of life. Thus, we can investigate and explain metabolic strategies of eukrayotic organisms in terms of competition for the limited resources at both individual protein- and compartment levels.