The Systems Bioinformatics section of the VU University in Amsterdam (NL) is offering a 3-year position for a
PhD student to study How a single cell integrates multiple signals via one of its G-protein coupled receptors
We are looking for a master student with a degree in systems biology, biophysics, or molecular biology who is highly motivated to pursue a PhD study. You should be highly interested in combining state-of-the-art fluorescence microscopy with theoretical methods to understand how single human cells integrate signals via one of its G-protein coupled receptors (GPCRs) and its downstream signalling network. You will be working with FRET-sensors, which monitor the activation of particular G-proteins upon GPCR activation, and fluorescent reporters of downstream signalling activity. Theoretical methods from systems biology and biophysics shall be used for data analysis, mechanistic understanding and predictive modelling.
This project is part of the European Marie Curie ITN project “CaSR Biomedicine”. It combines the expertise of about 10 EU-research labs that aim to understand the role of the calcium sensing receptor, a GPCR, from protein to patient level. This vacancy is at the section Systems Bioinformatics (www.teusinklab.nl, VU University, Amsterdam, The Netherlands) and the Molecular Cytology lab (www.molecularcytology.nl, University of Amsterdam, The Netherlands). Students are only eligible if at the time of the selection by the host university, the candidate has not resided or carried out their main activity (work, studies, etc) in the Netherlands for more than 12 months in the 3 years immediately prior to the starting date.
Please send your CV (including your grade list) and the contact information of two previous supervisors to Prof Dr Frank J Bruggeman (firstname.lastname@example.org).
For additional information see: