Lab News

We published a new review paper on phenotypic variability

Go and see it here, we hope you like it! We tried to give a fairly comprehensive overview of some of the mechanisms underlying phenotypic variation and diversification in populations of microorganisms and how phenotypic variation influences fitness.

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Amsterdam Biohackathon – De Waag July 8th & 9th

On July 8th and 9th, de Waag will open its doors for the first Amsterdam Biohackathon, organised by digi.bio. We will get our hands on programmable microfluidic devices, digital biology, and artificial intelligence. Want to know more? Here is the official website.

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Lab retreat 2017 was a great success

We all moved for three days to Groesbeek for our yearly lab retreat, this year organised by three new PhD students, Eunice, Daan and Sieze. They did a wonderful job: many people introduced a problem in the morning, from technical (how to model complex communities) to more evolutionary (why do lactic acid bacteria make flavours?),

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paper by Johan got three stars recommendation at F1000

Herbert Sauro, systems and synthetic biologist from University of Washington, Seattle, recommended the 2015 BioEssays review that Johan wrote together with Frank and Bas, saying it is an essential read for biochemistry textbook writers. The review is about the regulation of glycolysis, explained from a functional supply-demand perspective. See for the recommendation text. Thanks for the

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Another theorist went to the wet/dark side

Another theorist has been spotted in the lab yesterday. Daan de Groot, in the picture trying to pipet water into a tube with the cap still on, will try to validate a theoretical prediction. Coco van Boxtel, everybody’s favorite red-haired lab worker, will guide him through the process, thereby ensuring upcoming successes. The first success

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Iraes Rabbers wins the AIMMS PhD competition

On the 13th of April, our institute, the Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), organised its annual symposium with a PhD student contest for best talk of the day. Iraes Rabbers presented her thesis work on the optimality of protein expression in E coli, and won! Congrats Iraes, well done!

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We are organising a meeting on Systems Biology of Metabolic Regulation

On March 28 we have an exciting number of presentations scheduled by yeast experimentalists and theoretical systems biologists trying to work out the underlying principles of metabolic regulation. You are welcome to attend this meeting. For more information, go and see the meeting information here.

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Our master in Bioinformatics and Systems Biology is TOP!

In the latest results from the National Student Enquete (Inquiry) NSE our master got an 8.2 out of 10, and this makes it officially a TOP master, one of only 6 TOP masters at the VU. The master is a joined effort of Systems Bioinformatics and Bioinformatics from the VU, and the Life Science groups from the

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First recommendation for F1000 published

Bas was asked to contribute recommendations to the Faculty of 1000, and group members can nominate papers, and help write the recommendation – and get the credits. This month’s recommendation can be seen here. Article details: Dynamic control of gene regulatory logic by seemingly redundant transcription factors. Z AkhavanAghdam, J Sinha, OP Tabbaa and N

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Jurgen published a new paper on Network-based drug design in Scientific Reports

Jurgen published a paper from his postdoc in the labs of Prof. Barbara Bakker (UMCG) and Hans Westerhoff (Molecular Cell Physiology, AIMMS, VU) What it is about: To avoid side-effects of drug treatment to healthy cells, drug target selection studies often focus on protein targets that are only found a disease-causing cell. However, many disease-causing

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