Biogenesis, maintenance and dynamics of glycosomes in trypanosomatid parasites

Highlights

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Glycosomes are specialized peroxisomes in protists of the taxon Kinetoplastea

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Glycosomes compartmentalize enzymes of glycolysis and some other metabolic processes

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Compartmentation compensates for a lack of feedback regulation of glycolytic enzymes

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Glycosome turnover and dynamics play important roles in remodelling of metabolism

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A glycosome-targeted phosphatase participates in lifecycle differentiation signalling